Impact of Neuro-Behçet Disease Immunoglobulin G on Neuronal Apoptosis

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Impact of Neuro-Behçet Disease Immunoglobulin G on Neuronal Apoptosis.

INTRODUCTION Parenchymal neuro-Behçet disease (NBD) is encountered in 5%-15% of Behçet disease (BD) patients and is characterized by inflammation of the brainstem and diencephalon structures. Neuronal apoptosis has been shown to participate in neuronal cell loss. Anti-neuronal antibodies have been identified in NBD patients. However, the pathogenic properties of these antibodies have not been s...

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Neuro-neutrophilic disease: neuro-Behçet disease and neuro-Sweet disease.

“Neuro-Sweet disease (NSD)” was proposed as a distinct entity of encephalomeningitis in 1999 (1). Sweet disease has been considered as a multisystem inflammatory disorder characterized by painful erythematous plaques, and has been classified as a dermatologic disease. The plaques respond to systemic corticosteroids, and heal without scarring. It has been disclosed that aseptic neutrophilic infl...

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Neuro-Behçet disease mimicking brain tumor.

Neuro-Behcet disease is one of the clinical forms of Behcet disease. We report a case of neuro-Behcet disease mimicked a brain tumor. This case was initially considered as a brain tumor from mass lesion with edema at left basal ganglia on radiologic images. The lesion, however, was not neoplasia by pathologic diagnosis. By using steroid therapy, the size had been markedly shrunken on the follow...

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A Case of Bruton’s Disease with Normal Immunoglobulin G Level

X-linked agamaglobulinemia (XLA) or Bruton’s disease is a genetic disease resulting from a mutation in the Bruton’s tyrosine kinase (Btk) gene. This mutation leads to B cell arrest during differentiation (1). This disease was first described by Ogden Bruton in 1952 (2). Approximately 85% of the affected subjects are male (3). This disorder is inherited as an X-linked recessive trait. Carrier fe...

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Unusual Late Onset of Parenchymal Neuro-Behçet Disease

Neuro-Behçet disease (NBD) is a multisystem inflammatory disorder characterized by oral lesions, genital lesions, uveitis, and neurological deficits. If left untreated, it may lead to worsening neurological function and can be fatal. Here we present a case of a 52-year-old woman who was diagnosed with Behçet disease (BD) as a teenager and had a relatively mild disease course. Decades later afte...

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ژورنال

عنوان ژورنال: Noro Psikiyatri Arsivi

سال: 2017

ISSN: 1300-0667,1309-4866

DOI: 10.5152/npa.2016.19421